跳至主要内容
临床试验/CTRI/2025/09/094336
CTRI/2025/09/094336尚未招募2 期

A clinical study to eveluvate the efficacy of injection therapy and apamarga kshara in arshas

Dr UDAYAN BHADRA1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年10月1日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
To analyse the reduction in size of arshas, pain and difficulty while defecation,

研究概览

简要总结

Arshas which is compared to haemorrhoids in the contemporary science is the commonest   ano-rectal condition seen in the practice of proctology. The dilated veins within the anal canal in the sub-epithelial region formed by radicles of superior, middle and inferior rectal veins are called as Haemorrhoids. Incidence of this disease can be traced since Vedic period. Its incidence increases with advancing age, at least 50% of people over the age of 50 years have some degree of haemorrhoidal symptoms. Now a day’s most of the persons suffer from any one of the complaints of piles during their life time.

The ancient medical authorities like Acharya Charaka and Acharya Sushruta both have described four types of measures for the treatment of Arsha.These are Bheshaja, Kshara, Agni and Shastra. Acharya Sushruta speaks much about Kshara, Agni, Shastrakarma. While going through the chapter of treatment of the disease Arshas, it becomes quite evident that Kshara Karma has been indicated for all the varieties of Arshas, that even the pedunculated and Arsha of a very big size can also be successfully treated with the help of Kshara Karma. Hence the repeated advocacy of Kshara Karma by almost all the ancient Acharya in the disease Arshas has given an inspiration to work on the disease Arsha with the help of Pratisaraneeya Kshara, because of its simple technique and it has important properties like Chedana, Lekhana, Ropana.

Pratisaraneeya Kshara described as an upakrama, substitute for surgical instruments, can be used safely in patients who are afraid of surgery. The detailed description of many Kshara preparations are available in Susruta Samhitha.

According to modern surgery haemorrhoids, which are not treated properly or neglected, may lead to complication such as strangulation, thrombosis, portal pyaemia, suppuration, haemorrhage etc. The management of haemorrhoids in modern medical science is changing from conventional surgical procedure i.e., Haemorrhoidectomy to other procedures like Injection Therapy, Rubber band ligation, Cryosurgery, Laser therapy etc. Injection therapy is a form of sclerotherapy, where 5% Phenol with Almond oil is injected submucosally causing fibrosis in submucosal region and thereby fixation of the anal cushions which do not prolapsed.

Hence an effort is made to compare and evaluate the efficacy of Injection therapy and ApamargaPratisaraneeya Kshara in Arshas.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Patients above 18yrs and below 70 yrs of age.
  • Presence of signs and symptoms of Arshas.
  • No discrimination of gender, chronicity or socio economic status.
  • Patient ready to participate and sign the informed written consent.

排除标准

  • Patients below 18 yrs and above 70 yrs of age.
  • Patients with other serious systemic disorders
  • Contra-indications of Kshara Karma.
  • Contra-indications of Injection Therapy.
  • Pregnant and lactating women.

结局指标

主要结局

To analyse the reduction in size of arshas, pain and difficulty while defecation,

时间窗: 2 WEEKS(14 DAYS)

次要结局

  • Improving the quality of life in patients diagnoised with arshas(AFTER 14 DAYS)

研究者

发起方
Dr UDAYAN BHADRA
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr UDAYAN BHADRA

Institute

研究点 (1)

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