Improving iron status through consumption of cowpea: A stable isotope study

Completed

Conditions: minerale absorptie aandoeningen
iron absorption
iron bioavailability

Registration Number: NL-OMON33123

Lead Sponsor: Wageningen Universiteit

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 16

Inclusion Criteria

female
18-40 year
Weighing no more than 65kg
Non-pregnant, non-lactating
Apparently healthy free from chronic illness or receiving chronic medication
No medicinal nor supplemental iron at time of entry onto the study
No intake of vitamin or mineral supplements in the last 2 weeks prior the study, or willingness to discontinue.
Subjects has not made blood donations in the last 6 months
Subjects has not participated in studies using stable isotopic labels (iron) in the past.

Exclusion Criteria

younger than 18 years or older than 40
weighing more than 65kg
Use of mineral and vitamin supplements
People consuming chronic medication
pregnant or lactating
Blood donation inthe last 6 months
Participation to stable isotope studies (iron) in the past

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Iron absorption will be estimated using stable-isotope techniques where<br /><br>incorporation of 57Fe and 58Fe into erythrocytes is measured 14 d after<br /><br>administration. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Whole blood will be collected at recruitment for the analysis of Hb, serum<br /><br>ferritin (SF), C-reactive protein (CRP). Anemia will be defined as a hemoglobin<br /><br>concentration < 120 g/L, and iron deficiency will be defined as an SF<br /><br>concentration < 12 µg/L. </p><br>