The effectiveness of probiotics pills on microbial population in orthodontic patient
Phase 2
- Conditions
- Orthodontic.Fitting and adjustment of ileostomy and other intestinal appliancesZ46.5
- Registration Number
- IRCT20200203046363N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 75
Inclusion Criteria
Age of 17-18 years
No history of systemic disease
Nonuse of antibiotic and probiotic drugs
The patient is in the middle of the spectrum regarding caries risk, and not high caries risk is recommended. In addition, the individual should have good oral hygiene
Exclusion Criteria
Dentinogenesis imperfect
Amelogenesis imperfect
Having specific metabolic diseases
Bulimia nervosa
Anorexia nervosa
Having probiotics drug intolerance
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Buffering power of the saliva. Timepoint: Before and 3 weeks after the intervention. Method of measurement: PH meter device.;Streptococcus mutans population. Timepoint: Before and 3 weeks after the intervention. Method of measurement: Microbial counting.;Lactobacillus population. Timepoint: Before and 3 weeks after the intervention. Method of measurement: Microbial counting.
- Secondary Outcome Measures
Name Time Method