NCT04692545已完成不适用
Preoperative Immunonutrition Versus Standard Dietary Advice in Normo-nourished Patients Undergoing Fast-track Laparoscopic Colorectal Surgery
University of Rome Tor Vergata0 个研究点目标入组 173 人开始时间: 2016年12月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 173
- 主要终点
- Length of hospital stay
研究概览
简要总结
Immunonutrition (IN) appears to reduce infective complications and in-hospital length of stay (LOS) after gastrointestinal surgery. More specifically, it seems to be beneficial also in colorectal cancer surgery. Potential benefits of combining preoperative IN (PIN) with protocols of enhanced recovery after surgery (ERAS) in reducing LOS in laparoscopic surgery are yet to be determined.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •laparoscopic colorectal resection for cancer following ERAS protocol
- •>18 years old
- •elective setting
排除标准
- •age below 18
- •malnutrition
- •inflammatory bowel disease
- •acquired or congenital immunodeficiency
- •preoperative infection
- •pregnancy
- •emergency setting
- •conversion to open surgery
- •multivisceral resections
结局指标
主要结局
Length of hospital stay
时间窗: up to 30 days after discharge
number of days between primary colorectal resection and discharge
次要结局
- 30-days Mortality(up to 30 days after discharge)
- Pneumonia(up to 30 days after discharge)
- Time to postoperative food intake(up to 30 days after discharge)
- Time to first defecation(up to 30 days after discharge)
- 30-days postoperative complications(up to 30 days after discharge)
- Surgical site infection(up to 30 days after discharge)
- Anastomotic leak(up to 30 days after discharge)
- Readmission(up to 90 days after discharge)
- Ileus(up to 30 days after discharge)
- Prolonged length of stay(up to 30 days after discharge)
研究者
Giuseppe Sigismondo Sica
MD, PhD, Associate Professor
University of Rome Tor Vergata
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