Evaluation of Pain Reduction After Hemorrhoidectomy With Use of Diltiazim Ointment 2%

Phase 4

Completed

• Conditions: Pain
• Interventions: Drug: Diltiazem

• Registration Number: NCT00893100
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

The purpose of this study is to evaluate the effectiveness of diltiazem ointment 2 percent in reducing pain after hemorrhoidectomy.

Detailed Description

Pain after hemorrhoidectomy remains a major postsurgical complication.Therefore pain management in patients is an important goal.Many studies have focused on surgical techniques,preoperative and postoperative regimes.We assessed a randomised double blind placebo-controlled trial to evaluate the effect of diltiazem ointment after surgery.

Study Timeline

• Study Start: 2007-10
• Primary Completion: 2008-12
• Study Completion: 2008-12
• Study First Submitted: 2009-04-19
• Status Verified: 2009-05
• Study First Submitted QC: 2009-05-02
• Last Update Submitted: 2009-05-02
• Study First Posted: 2009-05-05
• Last Update Posted: 2009-05-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1

Inclusion Criteria

• Patients with grade 3 or 4 hemorrhoid who underwent Milligan-Morgan surgery.

Exclusion Criteria

• Patients with a history of heart disease, blood pressure, orthostatic hypertension, hemorrhoidal surgery,or those who had previous adverse effect from calcium channel blocker drugs and also those who were pregnant.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Diltiazem	Diltiazem	-

Primary Outcome Measures

Name	Time	Method
Reduction of Pain	daily in one week

Trial Locations

Locations (1)

Sina General Hospital; 🇮🇷 Tehran, Iran, Islamic Republic of