EVALUATION OF AN INNOVATIVE TREATMENT FOR RADIOCARPAL OSTEOARTHRITIS USING INTRA-ARTICULAR INJECTION OF A MIXTURE OF AUTOLOGOUS MICROFAT AND AUTOLOGOUS PLATELET-RICH PLASMA” - AMIPREP

ASSISTANCE PUBLIQUE HOPITAUX MARSEILLE0 个研究点目标入组 12 人开始时间: 2019年11月25日最近更新: 2021年8月24日

适应症

试验速览

暂无简介。

•-Males and females between 20 and 75 years of age
•-Symptomatic radio-carpal osteoarthritis diagnosed by arthroscanner resistant to medical treatment and candidate to surgery
•-BMI = 20 Kg/m²
•-Written informed consent, signed by patient or legal representative (if patient unable to sign).
•-HB > 10g/dl
•-Negative pregnancy test and efficiency contraception
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 8
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 4

•-Thrombocytopenia < 150 G/L, Thrombocytosis > 450 G/L, Thrombopathy
•-TP < 70%, TCA patient / witness rapport > 1,20
•-Anemia: HB < 10g/dl
•-Positive serology VIH1 and 2, Agp24, Ac HCV, Ag HbS, AcHbc, Ac HTLV I and II, TPHA
•-Treatment by platelet inhibiting agent, aspirin, antivitamin K completed more than 2 weeks before inclusion
•-Chronic treatment by corticosteroid per os or treatment completed more than 2 weeks before inclusion
•-Intra articular injection of corticosteroid or hyaluronic acid completed more than 8 weeks before inclusion
•-NSAI treatment completed more than 2 weeks before inclusion
•-Fever or recent disease completed more than 1 month before inclusion
•-Auto immune disease, Inflammatory or microcrystalline Arthritis, Immune deficit
•-Infectious disease
•-IRM contraindication: ocular loose bodies, pace maker, neurostimulator, cochlear implant, vascular clips, metallic cardiac val
•-Anesthesia or surgery contra indication, iodine allergy

发起方

ASSISTANCE PUBLIQUE HOPITAUX MARSEILLE