study to find abortion as a cause of Amavata (Rheumatoid arthritis)

Completed

Conditions: Rheumatoid arthritis with rheumatoid factor without organ or systems involvement,
apparently healthy females

Registration Number: CTRI/2022/02/040579

Lead Sponsor: Government of NCT of Delhi

Brief Summary: Clinically diagnosed patients of Rheumatoid Arthritis and apparently healthy females will be enrolled for study from OPD and IPD of Ch. Brahm Prakash Ayurved Charak Sansthan Khera Dabar, Najafgarh, New Delhi. Screening of patient will be carried out as per subjective and objective assessment criteria to diagnose *Aamvata* (Rheumatoid Arthritis).

After initial screening and assessment, the eligible patients will be enrolled in study and randomly divided into two groups.Clinically diagnosed patients of Rheumatoid Arthritis and apparently healthy females will be enrolled for study from OPD and IPD of Ch. Brahm Prakash Ayurved Charak Sansthan Khera Dabar, Najafgarh, New Delhi. Screening of patient will be carried out as per subjective and objective assessment criteria to diagnose *Aamvata* (Rheumatoid Arthritis).

After initial screening and assessment, the eligible patients will be enrolled in study and randomly divided into two groups.

Grouping: Total 100 number of female patients randomly enrolled in the study and divided into two groups, 50 numbers of patients in each group.

Group A: 50 female patients of Rheumatoid Arthritis.

Group B: 50 apparently healthy females.

Both seropositive and seronegative patients of Rheumatoid Arthritis will be taken.

Patients of RA will be included in group A and apparently healthy females will be included in B groups as per designing of case control study.

The selected patients shall undergo the series of events which includes their demographic details; informed consent about the study, a detailed history will be taken which could help in making the right diagnosis. Registration will be done and a detailed proforma will be filled as per the requirements of the study.

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Female

Target Recruitment: 100

Inclusion Criteria

Female patients between age group of 21-65 years.
Diagnosed patients of Rheumatoid Arthritis as per 2016 EULAR and ACR revised criteria.
Patients having Samanayalakshana and Pravridhalakshana of Amavata as per Madhavanidana.
Patients willing to give consent for the study.

Exclusion Criteria

Pregnant women and lactating mother.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To find out association of abortion in Rheumatoid arthritis patients and its severity on DAS-28 Scale at the time of filling of Case report form (CRF) .	9 months

Secondary Outcome Measures

Name	Time	Method
1. RA Factor Parameter will be assessd at the time of enrollement of the patients.	2. Functional parameters like Foot pressure,Grip strength and walking time will be assessed at the time of filling of case report form (CRF) on enrollement in the study.

Trial Locations

Locations (1): CH BRAHM PRAKASH AYURVED CHARAK SANSTHAN, NEW DELHI
🇮🇳
West, DELHI, India
CH BRAHM PRAKASH AYURVED CHARAK SANSTHAN, NEW DELHI
🇮🇳West, DELHI, India
Dr Umesh Kumar Sapra
Principal investigator
8588943505
umeshsapra123@gmail.com