Identfication of tumor-specific and tumor-associated antigens for potential clinical application in vaccination studies - Part: Squamous cell cancer of the head and neck

Recruiting

• Conditions: C10; Malignant neoplasm of larynx; C32; Malignant neoplasm of oropharynx

• Registration Number: DRKS00014018
• Lead Sponsor: niversitätsklinikum Tübingen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-02-14
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Squamous cell carcinoma of the head and neck with indication for surgical resection

Exclusion Criteria

- Relevant comorbidities
- no indication for surgery
- insufficient amount of tumor material

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Identification of HLA-presented tumor-associated and/or tumor-specific ligands (HLA-ligandome)

Secondary Outcome Measures

Name	Time	Method
- Evaluation of the immunological relevance of the identified ligands<br>- Evaluation of metabolic pathways