Evaluation of efficacy of prophylactic antibiotic therapy in prevention of incidence of meningitis in patient with basilar skull fracture and cerebrospinal fluid leakage
Not Applicable
- Conditions
- Fracture of base of skull due to trauma.Fracture of base of skull
- Registration Number
- IRCT2014123020485N1
- Lead Sponsor
- Ahvaz Jundishapour Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 346
Inclusion Criteria
(Selected patients suffered from traumatic base skull fractures with cerebrospinal fluid leakage characterized by rhinorrhea or otorrhea;All participants were at least 18 years old)
(Exclusion criteria: Patients with visible lesions on CT scans in need of surgery;patient with Depressed skull fracture, space-occupying lesions, signs of intracranial pressure increase;patients with cerebrospinal fluid disturbance and/ or meningitis; In cases with signs of meningitis such as fever, purulent discharge, meningismus)
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prevention of incidence of meningitis in patient with basilar skull fracture and csf leakage. Timepoint: TBI patient reffer to Golestan hospital of ahvaz in 2014-2015. Method of measurement: Analyse of csf obtain frome lumbar puncture.
- Secondary Outcome Measures
Name Time Method Incidence of meningitis. Timepoint: in course of admision. Method of measurement: with lumbar puncture and analyse of cerebrospinal fuid sample.