Analysis for the reactivation of hepatitis B virus (HBV) in rheumatoid arthritis or psoriasis patients with past HBV infection treated with anti-tumor necrosis factor-alpha therapy
Not Applicable
- Conditions
- rheumatoid arthritis or psoriasis patients with past hepatitis B virus infection
- Registration Number
- JPRN-UMIN000018017
- Lead Sponsor
- Department of general internal medicine, Kyushu-University hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Patients with severe infection such as sepsis. (2) Patients with active tuberculosis (3) Patients with history of demyelinating diseases such as multiple sclerosis (4) Patients with congestive heart failure (5) Patients who are pregnant or lactating women, and are women of childbearing potential (6) Patients with history of hypersensitivity to anti-tumor necrosis factor-alpha agents or nucleoside analogues (7) Patients with hepatitis C virus infection or human immunodeficiency virus-1 infection
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. The incidence of HBV reactivation in rheumatoid arthritis patients with past HBV infection treated with anti-tumor necrosis factor-alpha therapy. 2. The incidence of HBV reactivation in psoriasis arthritis patients with past HBV infection treated with anti-tumor necrosis factor-alpha therapy.
- Secondary Outcome Measures
Name Time Method