Effect of an alternative to suture in periodontal surgeries

Phase 2

• Conditions: Health Condition 1: K053- Chronic periodontitis

• Registration Number: CTRI/2019/02/017480
• Lead Sponsor: Dr Neha Pradhan

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Patients diagnosed with periodontitis, with good systemic health and presence of a minimum of 3 teeth with periodontal pocket depth (PPD) of >=6mm and clinical attachment level (CAL) of >=5mm (stage 3 periodontitis as described by the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Condition and published by the American Academy of Periodontology) in at least two quadrants will be selected.

Exclusion Criteria

1.Patients who have undergone periodontal therapy during the previous 6 months, or exhibit poor plaque control after phase I therapy.

2.History of any systemic disease such as diabetes mellitus, hypertension, osteoporosis, unstable or life-threatening conditions, bleeding disorder, undergoing antibiotic or other antimicrobial therapy.

3.Patients on drugs like aspirin, blood thinners and anticoagulant therapy

4.Patients with history of allergy

5.Current or former smokers.

6.Mobility of selected teeth.

7.Pregnant or lactating women.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cytokines Parameter for Interleukin 1-β will be assessed in GCF using a commercially available Enzyme-linked immunosorbent assay kit (ELISA), specific for human IL-1 βTimepoint: baseline <br/ ><br>7th day after treatment

Secondary Outcome Measures

Name	Time	Method
VAS Score by Freyd in 1923 <br/ ><br>Timepoint: baseline <br/ ><br>7th day <br/ ><br>14th day <br/ ><br>21st day <br/ ><br>28th day;Early Wound Healing Index by Watchel et al in 2005 <br/ ><br>Timepoint: baseline <br/ ><br>7th day <br/ ><br>14th day <br/ ><br>21st day <br/ ><br>28th day;Gingival Index by Loe and Silness in 1963 <br/ ><br>Timepoint: baseline <br/ ><br>7th day <br/ ><br>14th day <br/ ><br>21st day <br/ ><br>28th day;Oral Hygiene Index by John C Greene and Jack R Vermilion in 1964 <br/ ><br>Timepoint: baseline <br/ ><br>7th day <br/ ><br>14th day <br/ ><br>21st day <br/ ><br>28th day