Accuracy and Precision of Non-invasive Effective Pulmonary Perfusion Measurement Using Volumetric Capnography
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Accuracy and precision of capnodynamic to measure cardiac output
研究概览
简要总结
Cardiac output monitoring is mandatory in most surgical and critical care patients. Many techniques to assess cardiac output are invasive and/or have many limitations, contraindications and drawbacks. The measurement of cardiac output throughout the CO2 signal is an interesting option due to the simplicity and non-invasive nature of its calculation.
The present study was designed to compare the cardiac output measurement using a capnodynamic formula versus the reference thermodilution method.
详细描述
This is a prospective and observational study designed to test the accuracy and precision of the non-invasive capnodynamic cardiac output measurement in mechanically ventilated patients. We will study 30 patients undergoing cardiovascular by pass in which an invasive trans-thoracic thermodilution method (PICCOScience) is indicated - the reference method.
A pair of thermodilutions and capnodynamic cardiac output measurement will be performed along the surgery. Analysis of precision will be done at the begining of the protocol and during stable hemodynamic conditions. Accuracy will then assessed using the Bland-Altmann plot and regression analysis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Written informed consent
- •Programmed cardiac surgeries
- •Surgeries with cardiopulmonary bypass
排除标准
- •Emergency surgeries.
- •Acute pulmonary diseases
- •Contraindication of femoral catheters.
- •Need of counter-pulsation baloon
结局指标
主要结局
Accuracy and precision of capnodynamic to measure cardiac output
时间窗: 8 months
Comparison between a reference method (thermodilution) with a new one (capnodynamics)
次要结局
未报告次要终点