NCT05474391进行中（未招募）不适用
The Value of MammaPrint in Adjuvant Therapy Decision Among Pre-menopausal Breast Cancer Patients: a Survey Based on Clinical Staff
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Treatment decision survey
研究概览
简要总结
Nearly 200 cases are to be enrolled. The information of patient age, histologic grade, tumor size, ER and PR status, Ki-67 index, surgery mode should be provided. The adjuvant therapy regime (chemotherapy: none, TC*4, TC*6 or EC-T; endocrine therapy: TAM, OFS+TAM, OFS+AI) will be compared before and after MammaPrint testing. About 20 clinical staffs are enrolled to participate in this survey for the clinical decision making. Each case could be chosen five times at random.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- — 至 50 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •pre-menopausal breast cancer patients aged less than 50 years old.
- •Pathology confirmed invasive dutal carcinoma or invasive lobular carcinoma.
- •receiving breast conserving surgery or mastectomy with/without reconstruction; sentinel lymph node biopsy or axillary lymph node dissection.
- •TNM staging: T1b-T2N0-1M
- •molecular subtype: ER positive/HER2 negative.
- •MammaPrint testing before initiation of adjuvant therapy.
排除标准
- •Incomplete medical history.
- •Pregnancy or lactation.
- •Contradiction of chemotherapy or ovarian function suppression.
结局指标
主要结局
Treatment decision survey
时间窗: 6 weeks
Treatment decision change after MammaPrint testing
次要结局
未报告次要终点
研究者
研究点 (1)
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