Creatine Monohydrate Versus Creatine Hydrochloride on Strength and Body Composition in Elite Team-Sport Athletes
- Conditions
- Healthy Lifestyle
- Interventions
- Dietary Supplement: Creatine HydrochlorideDietary Supplement: Creatine MonohydrateDietary Supplement: Placebo
- Registration Number
- NCT05697900
- Lead Sponsor
- Dynamical Business and Science Society - DBSS International SAS
- Brief Summary
A triple-arm double-blinded placebo-controlled repeated-measures randomized clinical trial in Colombian elite team-sport athletes. The aim is to evaluate the effects on strength-related parameters and body composition after eight weeks of supplementation with creatine monohydrate (CrM) and creatine hydrochloride (Cr-HCl). The study will be reported following the Consolidated Standards of Reporting Trials (CONSORT) extension to Multi-Arm Parallel-Group Randomized Trials. All variables will be measured at baseline and after eight weeks.
- Detailed Description
Creatine monohydrate (CrM) is the most studied nutritional supplement and, therefore, one of the most popular ergogenic nutritional aids for athletes. Studies have shown that CrM supplementation increases intramuscular creatine concentrations which enhances exercise performance and improves body composition in different populations (from young athletes to older adults).
It is important to note that the U.S. Food and Drug Administration (FDA) have recognized CrM as a safe ingredient (Generally Recognized as Safe, GRAS - No. GRN 000931). In spite of this, other forms such as creatine chloride (Cr-HCl) have been marketed as a more bioavailable sources of creatine. Since there are not studies that rigorously compare the effects of CrM versus Cr-HCl on physical performance and body composition, the aim of this study is to evaluate the effects of a 8-week supplementation protocol with the two forms of creatine (comparing to placebo) on neuromuscular strength and body composition in Colombian elite team-sport athletes.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 48
- Practicing team sports at the competitive level (handball and softball)
- Having at least one year of competitive sports training experience (including strength training at least three times a week),
- Being attended at INDEPORTES Antioquia.
- Those who do not wish to participate voluntarily (do not sign informed consent),
- Those who were taking nutritional supplements (including creatine) eight weeks prior to the start of the study,
- Those who had a diagnosed pathology or health issues.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Creatine hydrochloride Creatine Hydrochloride 5 g of creatine hydrochloride per day for eight weeks Creatine monohydrate Creatine Monohydrate 5 g of creatine monohydrate per day for eight weeks Placebo Placebo 5 g of maltodextrin per day for eight weeks
- Primary Outcome Measures
Name Time Method Neuromuscular strength Eight weeks The load-velocity profile in squat and bench press exercises will be obtained with a linear position transducer (load in kilograms versus mean propulsive velocity in meters per second).
Upper-limb muscle strength Eight weeks Maximal shoulder external and internal strength will be measure with a isokinetic dynamometer.
Lower-limb muscle power Eight weeks Countermovement and drop jump will be performed on contact mat (height in centimeters and time of flight in seconds)
- Secondary Outcome Measures
Name Time Method Body composition Eight weeks Body composition was measured using dual-energy x-ray absorptiometry. Fat mass and lean mass in kilograms were reported.
Trial Locations
- Locations (1)
INDEPORTES Antioquia
🇨🇴Medellín, Antioquia, Colombia