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临床试验/NCT04654832
NCT04654832Unknown不适用

IVC Index in Patient With Diarrhea and Dehydration And How It Affects Its Management

Assiut University1 个研究点 分布在 1 个国家目标入组 57 人开始时间: 2020年10月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
57
试验地点
1
主要终点
(IVC Index in patient with Diarrhea and Dehydration and how it affects it's management.)

研究概览

简要总结

IVC Index in patient with Diarrhea and Dehydration And How It affects its management.

详细描述

Introduction The world health organization defines dehydration as condition that result from excessive loss of body water .the most common cause of dehydration in children are vomiting and diarrhea. Dehydration is a major cause of morbidity and mortality in infant and young children world wide .most cases due to consequence of acute gastroenteritis.

Pathophysiology. Dehydration cause decrease in total body water in both intracellular and extracellular fluid volume. Volume depletion closely correlate with sign and symptom of dehydration .the total body water is higher in infant and children compared to adult.

In infant, it is 70% of total body weight, whereas it is 65%and 60% respectively in children and adult.

The World Health Organization recommends assessing dehydration in children based on four clinical features: general appearance , eyes (whether they appear sunken), history of thirst , and skin pinch to assess turgor. However, these clinical signs may be subtle or non specific and thus have important limitations if used as independent predictors of dehydration. A more objective way to assess for dehydration using urine analysis has been implicated.

Additionally, studies on dehydration have shown urine analysis do not show sufficient sensitivity, Specificity or reliability [3, 4] and are typically only useful in children with moderate to severe hypovolemia.

研究设计

研究类型
Observational
观察模型
Case Crossover
时间视角
Cross Sectional

入排标准

年龄范围
1 Month 至 5 Years(Child)
性别
All
接受健康志愿者
是

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

(IVC Index in patient with Diarrhea and Dehydration and how it affects it's management.)

时间窗: IVC Index in patient with Diarrhea and Dehydration And How It affects its management21.(13). it expect it expected to be done from 1 October2020 till 29 December2021.(13)

Assessment of dehydration by ivc index and bcmanagement according to this index

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Reham Refaat abd elhafez

Assistant lecturer

Assiut University

研究点 (1)

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