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Clinical Trials/NCT03030807
NCT03030807
Completed
Not Applicable

Recognition of Pulmonary Hypertension in Patients With Hypersensitivity Pneumonitis

Medical University of Graz0 sites426 target enrollmentOctober 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pulmonary Hypertension
Sponsor
Medical University of Graz
Enrollment
426
Primary Endpoint
Prevalence of pulmonary hypertension
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The investigation serves the identification of pulmonary hypertension (PH) among patients with hypersensitivity pneumonitis (HP). The exact prevalence of PH in HP is unknown. Data from South America indicate that the prevalence of pre-capillary PH amongst patients with HP is higher than 20%. There are no reliable data from Europe so far. According to the investigators previous analysis, more than 400 HP patients have participated in pulmonary rehabilitation at least once in the past 10 years at Klinikum Bad Gleichenberg (Rehabilitation Center for Agricultural Workers in Austria). This collective of patients is to be invited to participate in the study.

A diagnostic algorithm will be applied in the clinical trial, in the case of clinical suspicion the diagnosis of PH will be confirmed by right heart catheterization. Besides the determination of the prevalence of PH in patients with HP the investigators aim to assess the reliability of non-invasive methods (e.g. Echocardiography, ECG...) to predict PH.

Registry
clinicaltrials.gov
Start Date
October 2016
End Date
October 31, 2020
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Medical University of Graz
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients with confirmed Hypersensitivity Pneumonitis
  • written consent
  • Age: 18-90 years

Exclusion Criteria

  • severe impairment of the general health condition
  • pregnancy

Outcomes

Primary Outcomes

Prevalence of pulmonary hypertension

Time Frame: 4 year

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