Endoprosthetic Replacement for Pathological Fractures of the Hip: A 35-year Update

Active, not recruiting

• Conditions: Hip Fractures; Hip Fracture Pathologic; Pathological Fracture; Pathological Fracture of Hip

• Registration Number: NCT06935071
• Lead Sponsor: Memorial Sloan Kettering Cancer Center

Brief Summary

This study will be based on a retrospective review of patients who received endoprosthetic reconstruction for pathologic fracture of the proximal femur. The objectives would be two-fold: (1) to compare rates ofambulation, pain, and survival to the historic cohort and (2) to identify predictors of ambulation in the current population.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-08-04
• Status Verified: 2025-04
• Study First Submitted: 2025-04-11
• Study First Submitted QC: 2025-04-11
• Last Update Submitted: 2025-04-11
• Study First Posted: 2025-04-18
• Last Update Posted: 2025-04-18
• Primary Completion: 2026-08-04
• Study Completion: 2026-08-04

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Participants have received endoprosthetic reconstruction for pathologic fracture of the proximal femur

Exclusion Criteria

• Participants with fractures greater than 3mm from the lesser trochanter
• Participants without histopathologic confirmation of tumor

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of rates of ambulation, pain, and survival to the historic cohort	up to 10 years	This study will be based on a retrospective review of patients who received endoprosthetic reconstruction for pathologic fracture of the proximal femur.

Trial Locations

Locations (1)

Memorial Sloan Kettering Cancer Center; 🇺🇸 New York, New York, United States