Safety of IntraOperative Cell Salvage in visceral ONcologic surgery
- Conditions
- visceral cancer
- Registration Number
- DRKS00033355
- Lead Sponsor
- niversitätsklinikum Heidelberg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
written informed consent by the patient
- elective visceral surgical tumor resection with suspected blood loss > 300 ml
Exclusion Criteria
- Infectious viral diseases (e.g. HBV, HCV, HIV, COVID-19)
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber of cancer cells in collected wound blood before and after cell salvage processing
- Secondary Outcome Measures
Name Time Method - Number of cancer cells in patient blood before and after cancer surgery<br>- Surface markers of CTCs, cancer cells from IOCS (intraoperative cell salvage) blood and the primarius <br>- Functional properties of CTCs, cancer cells from IOCS blood and the primarius (e.g. viability, migration and invasion assays)<br>- Gene expression of CTCs, tumor cells from IOCS blood and the main cancer