Effect of Laser and Potassium Nitrate Application on the Sensitivity Control in Bleached Teeth
- Conditions
- Dentin Sensitivity
- Interventions
- Drug: In-office dental bleachingDrug: Low Level Laser Therapy
- Registration Number
- NCT03434782
- Lead Sponsor
- Universidade Federal do Para
- Brief Summary
To investigate the effects of desensitizing agents on the dental bleaching process, testing the hypothesis that they may control dental sensitivity.
- Detailed Description
The objective of this double blind, randomized and controlled clinical study, was to evaluate the efficacy of potassium nitrate / sodium fluoride (KNO3 / KF) gel associated with LLLT (Low Level Light Therapy) on teeth that were exposed to 35% hydrogen peroxide during 3 weeks of bleaching treatment. Methods: 50 volunteers were evaluated through the split-mouth model, where the hemiarcates were randomized and later allocated in one of the experimental groups: G1 (negative control)- group with no desensitizing treatment, only bleached; G2 (positive control)- group treated with LLLT + placebo gel; G3- group treated with placebo laser application + 5% KNO3 / 2% KF gel; and G4- group treated with LLLT + 5% KNO3 / 2% KF gel.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
- Absence of active carious lesions;
- Never undergone bleaching therapy;
- Good oral hygiene;
- Do not present hypersensitivity;
- Do not smoke;
- Not being pregnant;
- Presence of at least 28 teeth in oral cavity.
- Presence of periodontal disease;
- Presence of cracks or fractures;
- Presence of restorations and prostheses;
- Presence of gastroesophageal dysfunction;
- Patients with severe internal dental dimming;
- Presence of periodontal disease;
- Presence of dentin exposure in anterior and/or posterior teeth.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description G2- LASER (Positive Control) In-office dental bleaching Group treated with placebo gel before bleaching and with LLLT after in-office bleaching. G2- LASER (Positive Control) Low Level Laser Therapy Group treated with placebo gel before bleaching and with LLLT after in-office bleaching. G1- Negative Control In-office dental bleaching Group with no desensitizing treatment. Prior to bleaching therapy, a water-soluble placebo gel, with non-active agent will be applied to dental vestibular surfaces. After bleaching therapy, the LASER tip will be positioned in two points (apical and cervical), without light emission (placebo). G3- KNO3 (Positive Control) In-office dental bleaching Group treated with desensitizing gel before bleaching and after in-office bleaching, the LASER tip will be positioned in two points (apical and cervical), without light emission (placebo). G4- KNO3 + LASER In-office dental bleaching Group treated with desensitizing gel before bleaching and with LLLT after in-office bleaching. G4- KNO3 + LASER 5% potassium nitrate / 2% sodium fluoride gel Group treated with desensitizing gel before bleaching and with LLLT after in-office bleaching. G3- KNO3 (Positive Control) 5% potassium nitrate / 2% sodium fluoride gel Group treated with desensitizing gel before bleaching and after in-office bleaching, the LASER tip will be positioned in two points (apical and cervical), without light emission (placebo). G4- KNO3 + LASER Low Level Laser Therapy Group treated with desensitizing gel before bleaching and with LLLT after in-office bleaching.
- Primary Outcome Measures
Name Time Method Change in Stimulated pain intensity in different assessment times (P15) 15 days, with assessments in the 1st, 8th and 15th day of the treatment The stimulated pain intensity was self reported by the patients with a modified visual analog scale, from 0 to 3, where 0 means "no pain", 1 is "mild pain", 2 is "moderate pain" and 3 is "severe pain". For all groups, the patients evaluated the stimulated pain intensity two times per session: before and after the treatment in the same day. Thus, in total each patient reported the pain intensity 6 times, two times in the first day (1st session), two times in the eighth day (2nd session) and two times in the fifteenth day (3rd session).
- Secondary Outcome Measures
Name Time Method Non-stimulated pain intensity measure, (P21) 21 days Self reported non-stimulated pain intensity was assessed daily, during 21 days, through self-perception questionnaire, answered by the patients from the first tooth bleaching session until one week after the last session. The evaluation was performed by each patient, according to a modified visual analog scale, as follows: 0- no pain, 1 mild pain, 2 - moderate pain and 3 -severe pain
Trial Locations
- Locations (1)
Brennda Lucy Freitas de Paula
🇧🇷Belem, Para, Brazil