Long-term Outcome of Punctate Inner Choroidopathy or Multifocal Choroiditis With Active Choroidal Neovascularization Managed With Anti-vascular Endothelial Growth Factor

Completed

• Conditions: Choroidal Neovascularization; Punctate Inner Choroidopathy

• Registration Number: NCT03793400
• Lead Sponsor: Changhua Christian Hospital

Brief Summary

To evaluate the long-term outcome of active choroidal neovascularization (CNV) in punctate inner choroidopathy (PIC) or multifocal choroiditis (MFC) after anti-vascular endothelial factor treatment.

Detailed Description

To evaluate the long-term outcome of active choroidal neovascularization (CNV) in punctate inner choroidopathy (PIC) or multifocal choroiditis (MFC) after anti-vascular endothelial factor treatment.

The age, sex, best corrected visual acuity (BCVA) in Snellen chart, and refractive status for each patient were recorded. All patients had thorough clinical examinations, including slit lamp biomicroscopy, indirect ophthalmoloscopy, and spectral domain optical coherence tomography during each visit. Fundus photography, fluorescein angiography, and indocyanine angiography were performed on all patients. OCT angiography was performed.

Study Timeline

• Study Start: 2018-03-13
• Primary Completion: 2018-04-13
• Study Completion: 2018-12-28
• Status Verified: 2019-01
• Study First Submitted: 2019-01-01
• Study First Submitted QC: 2019-01-02
• Study First Posted: 2019-01-04
• Last Update Submitted: 2019-01-06
• Last Update Posted: 2019-01-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

1. Patients were punctate inner choroidopathy or multifocal choroiditis with active choroidal neovascularization.
2. Follow up over 4 years.

Exclusion Criteria

1. Patients were not punctate inner choroidopathy or multifocal choroiditis with active choroidal neovascularization
2. Patients were punctate inner choroidopathy or multifocal choroiditis with active choroidal neovascularization but loss follow over 1 year.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Wilcoxon Signed-Rank test	Baseline,48 month.	A statistical comparison of average of two dependent samples

Secondary Outcome Measures

Name	Time	Method
visual acuity	Baseline,48 month.	visual acuity in logMAR

Trial Locations

Locations (1)

Changhua Christian Hospital; 🇨🇳 Changhua, Taiwan