TCTR20160413001已完成未知
Effect of continuous positive airway pressure on airway inflammation and oxidative stress in patients with obstructive sleep apnea
Faculty of Medicine, Khon Kaen University0 个研究点目标入组 15 人开始时间: 2016年4月13日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 15
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 30 Years 至 70 Years（—）
- 性别
- All
入选标准
- •Twenty-four patients whose age was between 30 to 70 years old volunteered to participate in the study. Patients were treated with CPAP while sleeping at night for at least five hours per night for at least five days per week for three consecutive months. Patients were diagnosed with OSA by medical specialists using polysomnography (PSG) within the month preceding the start of the study. Patients included in this study had an arousal index (AI) of at least 15/h and no history of cardiovascular disease (e.g. coronary heart disease and myocardial infarction).
排除标准
- •Patients with a history of autoimmune conditions or symptoms of respiratory tract infection in the six weeks prior to the study, history of sleep apnea treatment with CPAP or oral devices, tracheostomy, or use of oxygen therapy at home were excluded. Study subjects with history of other diseases associated with high FeNO (e.g. viral respiratory tract infections, systemic lupus erythematosis, liver cirrhosis, acute lung allograft rejection, and post-transplant bronchiolitis obliterans) or history of other diseases associated with low FeNO (i.e. cystic fibrosis, HIV infection and pulmonary hypertension) were excluded as well.
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