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The use of Myfortic in paediatric patients after liver transplantatio

Phase 1
Conditions
iver transplantation
Registration Number
EUCTR2005-001830-34-GB
Lead Sponsor
King's College Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
Not specified
Target Recruitment
4
Inclusion Criteria

Group 1: high risk for kidney dysfunction or pre-existing kidney dysfunction (GFR <80 ml/min/1.73m2). This inlcudes but is not limited to childen transplanted for hepatoblastoma, Alagilles syndrome, cystic fibrosis, alpha-1-antitrypsin deficiency, hyperoxuluria. The child is able to swallow tablets whole

Group 2: The child is experiencing gastrointestinal side effects of MMF requiring it to be reduced. The child is able to swallow tablets whole.
Are the trial subjects under 18? yes
Number of subjects for this age range:
F.1.2 Adults (18-64 years) no
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Parental consent and child assent has not been ascertained, pregnancy (all sexually active girls >12 years will have a pregnancy test prior to starting the study drug); hypersensitivity to mycophenolate

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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