Association of human herpesvirus 6 (HHV-6) and risk factors with depressio
- Conditions
- The patients who were diagnosed with major depressive disorder (MDD) by DMS-5 criteriaDepression, Human herpesvirus 6/HHV-6, Risk factors
- Registration Number
- TCTR20230829003
- Lead Sponsor
- /A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 229
Inclusion Criteria
1. The patients who were diagnosed with major depressive disorder (MDD) by DMS-5 criteria or ICD-10
Exclusion Criteria
1. Current diagnoses of other psychiatric disorders, 2. A severe depressive episode with psychotic symptoms, 3. Neurological diseases (Alzheimer's, Parkinson's, etc.), 4. Acute viral infection (HSV, VZV, CMV, etc.), 5. Autoimmune disease (rheumatoid arthritis, multiple sclerosis, asthma, etc.), 6. Chronic diseases (cancer, diabetes, heart disease, etc.) 7. Endocrine and metabolic diseases (Hypothyroidism, Hyperthyroidism, hyperparathyroidism, hypopituitarism, Addison disease, Cushing Syndrome) 8. Nutritional Disease (pellagra, pernicious anemia) 9. Hemophilia
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method HHV-6 infection at 12 months Real-time PCR
- Secondary Outcome Measures
Name Time Method Risk factors at 12 months Questionnaire interviews (lifestyle, family history, clinical history, nutrition, patient health questionnaire-9 (PHQ-9), patient health questionnaire-2 (PHQ-2), stress test questionnaire (ST-5) )