Gene expression and immunohistochemistry analysis of soft tissue covering bone grafted with xenograft in human

Office of Research Affairs, Faculty of Dentistry, Chulalongkorn University0 个研究点目标入组 16 人开始时间: 2024年6月20日最近更新: 2024年8月19日

适应症

试验速览

阶段: 不适用
状态: 进行中（未招募）
发起方
入组人数: 16

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

The result shows that the relative gene expression of TNF-a, IL-6, IL-8, and NF-kB1 are not significantly different in soft tissue covering xenograft compared to the ones in soft tissue covering normal bone healing.

研究设计

研究类型: Observational

入排标准

年龄范围: N/A (No limit) 至 N/A (No limit)（—）
性别: All

入选标准

•1.In the bone grafting group, subjects must have bone grafting using xenograft.
•2.All of subjects must have implant placements using The Straumann Dental Implant, Basel, Switzerland.
•3.A period of at least 3 months between extraction and implant placement.
•4.All of subjects must have enough excess soft tissue after implant placement that can be collected without interfering the normal treatment protocol.

排除标准

•1.The risk factors that affect soft tissue inflammation including uncontrolled diabetes, uncontrolled periodontal disease, previously peri-implantitis, or smoking.
•2.Use of antibiotics, anti-inflammatory drugs, or local antimicrobial agents within the former 6 months.
•3.Subjects that do not have enough excess soft tissue after implant placement which the collecting process will interfere the normal treatment protocol.

研究者

发起方

Office of Research Affairs, Faculty of Dentistry, Chulalongkorn University

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