Clinical outcome and safety of neuromodulation for severe traumatic brain injury in terms of neurological recovery
- Registration Number
- TCTR20240325005
- Lead Sponsor
- Phramongkutklao hospital foundation
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 68
1. all the adult patients with severe disability (GOS of 2 and 3) after trauma or stroke
2. Age more than 20 years
3. Patients have focal neurological deficits presenting with magnetic resonance imaging (MRI) brain or computed tomography (CT) head suggestive of MCA territory AIS presenting within 24 hour of symptom onset, National Institute of Health Stroke Scale (NIHSS) score of >4 and with a modified Rankin Scale (mRS) score of 0 or 1 before the stroke were included in this study.
Patients with brainstem strokes, transient ischemic attacks, brain tumor, demyelinating diseases, inflammatory diseases, craniotomies, hepatic failure, congestive heart failure, acute myocardial infarction, pregnancy and lactation, systemic malignancy, acute or chronic renal failure, and known allergy to above group of drugs.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eurological outcome 6 months modified ranking score at 6 months
- Secondary Outcome Measures
Name Time Method disability improve ment 6 months NIHSS and BI scores at 6 months