Comparative Study of Femtosecond Laser-assisted LASIK and Single-step Transepithelial Photorefractive Keratectomy for Correction of Mixed Astigmatism
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 39
- 试验地点
- 1
- 主要终点
- Uncorrected distance visual acuity (UDVA)
研究概览
简要总结
Mixed astigmatism is a type of refractive error in which the two principal steep and flat meridians focus the light in front and behind the retina, respectively.1 Laser vision correction (LVC) for mixed astigmatism is challenging as it involves a bitoric ablative pattern to flatten the steepest meridian and steepen the flattest one. The aim of the current study was to compare the visual and refractive outcomes of FS-LASIK versus single-step TransPRK for treatment of patients with mixed astigmatism.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Mixed astigmatism (Plus sphere up to +4 diopters D and a minus cylinder up to -6 D).
- •Stable refraction.
- •Clear cornea.
- •Normal corneal tomography.
排除标准
- •Corrected distance visual acuity worse than 20/32 Snellen's acuity.
- •Difference between manifest and cycloplegic refraction ≥ 1 D.
- •Previous corneal or ocular surgeries, other ocular diseases.
- •Systemic diseases including diabetes mellitus and autoimmune diseases.
研究组 & 干预措施
Femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) group
干预措施: Femtosecond laser-assisted LASIK (Procedure)
Single-step transepithelial photorefractive keratectomy (TransPRK) group
干预措施: Single-step transepithelial PRK (Procedure)
结局指标
主要结局
Uncorrected distance visual acuity (UDVA)
时间窗: 24 months
Visual acuity measurement using Snellen's Acuity Chart converted to logMAR notation.
Corrected distance visual acuity (CDVA)
时间窗: 24 months
Corrected visual acuity measurement using Snellen's Acuity Chart and converted to logMAR notation.
Postoperative refraction
时间窗: 24 months
Manifest sphere and cylinder measured by Topcon Auto-Keratorefractometer
次要结局
未报告次要终点
研究者
Mahmoud Abdel-Radi
Professor
Assiut University