Assessment of Endometrial Pattern and Sub-endometrial Vascularity in Prediction of Pregnancy Rate in ICSI
试验速览
- 阶段
- 不适用
- 入组人数
- 120
- 试验地点
- 2
- 主要终点
- The number of patients who will have positive pregnancy rate
研究概览
简要总结
Despite constant progress in in vitro fertilization (IVF) techniques and ovarian stimulation, pregnancy and embryo implantation rates remain modest . The phenomenon of embryo implantation depends both on the embryo itself and on endometrial receptivity
详细描述
A favorable uterine medium is necessary for embryo implantation, but endometrial receptivity can be negatively affected by ovarian stimulation . Study of endometrial receptivity is especially limited in the context of IVF cycles .
Biopsy of the endometrium cannot be considered during the treatment, and this has encouraged the development and use of ultrasonography and Doppler-like non-invasive methods to evaluate ovarian response to the stimulation and uterine receptivity .
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Maternal age from 20 to 40 years. Women with BMI range from 20 - 35 Women diagnosed with primary infertility
排除标准
- •Maternal chronic medical disorder (diabetes mellitus or hypertension). Women diagnosed with autoimmune diseases or antiphospholipid syndrome
结局指标
主要结局
The number of patients who will have positive pregnancy rate
时间窗: within 2 months
patients who will get pregnant in ICSI cycle with measuring their doppler indices before ovum pick up
次要结局
未报告次要终点