Assessment of Endometrial Pattern and Sub-endometrial Vascularity in Prediction of Pregnancy Rate in ICSI
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Infertility
- Sponsor
- Aljazeera Hospital
- Enrollment
- 120
- Locations
- 2
- Primary Endpoint
- The number of patients who will have positive pregnancy rate
- Last Updated
- 7 years ago
Overview
Brief Summary
Despite constant progress in in vitro fertilization (IVF) techniques and ovarian stimulation, pregnancy and embryo implantation rates remain modest . The phenomenon of embryo implantation depends both on the embryo itself and on endometrial receptivity
Detailed Description
A favorable uterine medium is necessary for embryo implantation, but endometrial receptivity can be negatively affected by ovarian stimulation . Study of endometrial receptivity is especially limited in the context of IVF cycles . Biopsy of the endometrium cannot be considered during the treatment, and this has encouraged the development and use of ultrasonography and Doppler-like non-invasive methods to evaluate ovarian response to the stimulation and uterine receptivity .
Investigators
Eligibility Criteria
Inclusion Criteria
- •Maternal age from 20 to 40 years. Women with BMI range from 20 - 35 Women diagnosed with primary infertility
Exclusion Criteria
- •Maternal chronic medical disorder (diabetes mellitus or hypertension). Women diagnosed with autoimmune diseases or antiphospholipid syndrome
Outcomes
Primary Outcomes
The number of patients who will have positive pregnancy rate
Time Frame: within 2 months
patients who will get pregnant in ICSI cycle with measuring their doppler indices before ovum pick up