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Clinical Trials/NCT04097847
NCT04097847
Completed
Not Applicable

Osteoradionecrosis and PENTOCLO Protocol: Retrospective Study.

University Hospital, Brest1 site in 1 country96 target enrollmentJune 2, 2017
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ConditionsOsteoradionecrosis of Jaw
DrugsPentoxifylline-Tocopherol-Clodronate

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Osteoradionecrosis of Jaw
Sponsor
University Hospital, Brest
Enrollment
96
Locations
1
Primary Endpoint
Clinical evolution of the osteoradionecrosis lesion after introducing PENTOCLO protocol
Status
Completed
Last Updated
6 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

osteoradionecrosis (ORN) affects up to 30% of irradiated patients and can occur up to several decades after stopping treatment. Differents therapeutics exist but there is no consensus concerning the management of the maxillary ORN. The understanding of new pathological mechanisms opens the way to new therapeutic perspectives.

Registry
clinicaltrials.gov
Start Date
June 2, 2017
End Date
April 1, 2019
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •Patient over 18 being or having been treated by pentoclo combination for an osteoradionecrosis of the jaw

Exclusion Criteria

  • •Tumoral recidivism
  • •Precocious stop of pentoclo

Outcomes

Primary Outcomes

Clinical evolution of the osteoradionecrosis lesion after introducing PENTOCLO protocol

Time Frame: 2 years

Retrospective study based on recovering patient data from medical records

Study Sites (1)

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