Pilot Study to Characterize the Microbiome in Cutaneous T Cell Lymphoma Skin Lesions Before and After Use of CLn® Skin Care Body Wash
Not yet recruiting
- Conditions
- Cutaneous T Cell Lymphoma
- Registration Number
- NCT06665490
- Lead Sponsor
- Northwestern University
- Brief Summary
In this pilot study of patients with mycosis fungoides, the most common form of CTCL, we propose to primarily evaluate the impact of daily use of the CLn Body Wash (dilute sodium hypochlorite (0.006% NaOCl)) on the microbiota of CTCL lesions. Should dilute sodium hypochlorite body wash improve the microbiome of MF, reducing the abundance of S. aureus, future, larger studies can more fully evaluate the impact on pruritus, erythema, scaling, disease evolution and its role in CTCL management.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 15
Inclusion Criteria
- Adults ages 18-89 years of age with active mycosis fungoides.
- Patients with concurrent and prior malignancies are allowed as long as any concurrent malignancy does not directly involve the same skin site.
Exclusion Criteria
- Patients currently or recently (within past 4 weeks) on topical or systemic antibiotics, pregnant persons, or persons with potential of becoming pregnant or are/will be breastfeeding
- Patients that have initiated a new skin-directed therapy over the past month.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction of S. aureus skin microbiome 8 weeks Reduction of S. aureus relative abundance between baseline (Week 0) and Week 8.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Northwestern University Department of Dermatology
🇺🇸Chicago, Illinois, United States