The Relationship between Sleep Quality and Target Effect-site Propofol Concentration during Transvaginal Oocyte Retrieval

Not Applicable

Completed

• Conditions: Sleep quality; Propofol required during Transvaginal Oocyte Retrieval; Anaesthesiology - Anaesthetics; Reproductive Health and Childbirth - Fertility including in vitro fertilisation

• Registration Number: ACTRN12615000505505
• Lead Sponsor: Changhua Christian Hospital, Taiwan (R.O.C.)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-05-20
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

Female patients assessed as the American Society of Anesthesiologists (ASA) physical status classification system class I and II who are ready for transvaginal oocyte retrieval

Exclusion Criteria

(1) refusal to provide informed consent,
(2) allergy to intravenous propofol, fentanyl, or lidocaine,
(3) hepatic, renal, or neurological dysfunction

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Relationship between sleep quality measured by using Pittsburgh Sleep Quality Index and the TCI effect-site concentrations of propofol required for loss of consciousness (loss of response to verbal commands) recorded by TCI device.[Pittsburgh Sleep Quality questionnaire completed by the patients before the procedure and target effect-site propofol concentration recorded at the time of anesthesia induction]

Secondary Outcome Measures

Name	Time	Method
Total propofol comsuption recorded by a TCI device[At the end of the transvaginal oocyte retrieval];Total sedation time recorded by a timer. Sedation begins when the patients lose response to verbal commands and ends when the patient could react to verbal commands.[At the end of the transvaginal oocyte retrieval];Post-procedure complication including nausea, vomiting,and pruritus observed by nurse in post anesthesia care unit. A phone interview will be performed after the patient goes home.[within one week after the intervention];Emergence time recorded by a timer. Emergence time was defined as the time required for the patient to react to verbal commands after TCI was stopped.[At the end of the transvaginal oocyte retrieval]