Prism Adaptation Therapy for Spatial Neglect

Not Applicable

• Conditions: Spatial Neglect; Deficits in Attention Motor Control and Perception
• Interventions: Behavioral: Prism Adaptation Treatment

• Registration Number: NCT00989430
• Lead Sponsor: Kessler Foundation

Brief Summary

The purpose of this research study with a randomized controlled design is to examine the effects of prism adaptation treatment on two visual-spatial recovery components. After a stroke, an "internal GPS", locating where objects or people lie in a particular area of space, may be impaired. Alternately, a stroke may impair precise visual-spatial hand and body aiming movements. The research team wishes to discover whether prism adaptation treatment (two weeks of daily 20-min sessions of goal-directed movement with prism goggles) affects visual-spatial where or aiming errors selectively after stroke.

This research represents one of the first attempts to apply what we know about the brain from neuroscience research, to modern clinical rehabilitation practices.

Detailed Description

The purpose of this research study with a randomized controlled design is to examine the effects of prism adaptation treatment on two visual-spatial recovery components. After a stroke, an "internal GPS", locating where objects or people lie in a particular area of space, may be impaired. Alternately, a stroke may impair precise visual-spatial hand and body aiming movements. The research team wishes to discover whether prism adaptation treatment (two weeks of daily 20-min sessions of goal-directed movement with prism goggles) affects visual-spatial where or aiming errors selectively after stroke.

This research represents one of the first attempts to apply what we know about the brain from neuroscience research, to modern clinical rehabilitation practices.

Study Timeline

• Study First Submitted: 2009-10-02
• Study First Submitted QC: 2009-10-02
• Study First Posted: 2009-10-05
• Study Start: 2012-10
• Status Verified: 2021-02
• Last Update Submitted: 2021-02-16
• Last Update Posted: 2021-02-17
• Primary Completion: 2021-10
• Study Completion: 2021-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

• The subject is 18 to 100 years of age, inclusive.
• The subject has had a stroke on the right side of the brain.
• The subject is able to give Informed consent.
• The subject has a spatial neglect (if known).
• The subject is able and willing to comply with the study protocol, including availability for all scheduled clinic visits.

Exclusion Criteria

• The subject has or had a serious brain condition other than stroke.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Prism Adaptation Treatment	Prism Adaptation Treatment	Two weeks of prism adaptation treatment followed by 4 weekly assessments and long-term follow-ups at the 3rd and 6th months.

Primary Outcome Measures

Name	Time	Method
Kessler Foundation Neglect Assessment Process	6 months	a performance based and behavioral measure for spatial neglect that utilizes and standardizes the administration of the Catherine Bergego Scale (CBS)

Secondary Outcome Measures

Name	Time	Method
Behavior Inattention Test	2 weeks	Conventional subtest, a set of paper and pencil test for spatial neglect
Barthel Index	2 weeks	A functional independence assessment of daily tasks

Trial Locations

Locations (1)

Kessler Institute for Rehabilitation; 🇺🇸 West Orange, New Jersey, United States