To compare efficiency of fentanyl vs low dose ketamine with dexmedetomidine as analgesic in patients with midline incision using IV patient controlled analgesia pump
Not Applicable
- Conditions
- Health Condition 1: K261- Acute duodenal ulcer with perforation
- Registration Number
- CTRI/2019/07/020292
- Lead Sponsor
- Dr RPGMC TANDA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA 1and 2
Undergoing exploratory laparotomy
BMI 18.5-29.9
Non opioid dependant
Exclusion Criteria
Patients refusal
Patient with known drug allergy
Opioid dependence
Hepatic and renal pathologies
History of long term usage of NSAIDS
Diabetes mellitus and other neuropathic disorders
Psychiatric disorders
Inability to use PCA pump
History of chronic pain
History of postoperative nausea and vomiting
History of motion sickness
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study and compare the quality of postoperative analgesia in two groups. <br/ ><br>To calculate the amount of drug consumed in each groupTimepoint: VRS less than 4 in 24 hours post operative
- Secondary Outcome Measures
Name Time Method To assess the requirement of rescue analgesic. <br/ ><br>To assess sedation and PONV by different drug combinations <br/ ><br>To assess patient satisfaction <br/ ><br>To assess hemodynamic parameters in the post operative period <br/ ><br>To assess side effects of drug combinations usedTimepoint: PONV 0-1 <br/ ><br>RSS 1-2 <br/ ><br>Patient satisfaction score 1-2 at 15min 30 min 1 hr 6 hours 12 hours and 24 hours post operatively