NL-OMON56478尚未招募不适用
Getting insight in the exposure effect relationship of Elexacaftor/ Tezacaftor/Ivacaftor treatment in people with cystic fibrosis - The exposure effect relationship of ETI treatment in pwCF
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •In order to be eligible to participate in this study, a subject must meet all
- •of the following criteria:
- •1.Cystic fibrosis based on DBC code ( specialisme: 0322 ; Diagnose: 1403)
- •2.Use of Kaftrio tablets with dosage of 75/5-/100mg and ATC code: R07AX32
- •3.Use of standard dose of ETI (2 tablets in the morning) and Ivacaftor (1
- •tablet in the evening).
- •4.Availability of a baseline and on ETI treatment sweat chloride value
- •5.A homozygous F508del mutation in the CFTR gene
- •6.A stable clinical condition defined as no pulmonary exacerbation in a period
- •of 4 weeks before study visit
排除标准
- •A potential subject who meets any of the following criteria will be excluded
- •from participation in this study:
- •1. Solid organ transplantation
- •2. The use of concomitant medications with CYP3A4 interactions during the
- •period of determining the trough concentration of ETI
- •3. Pregnancy
- •4. Liver cirrhosis
研究者
相似试验
已完成
Unknown
Environmental risk factors for psoriasis and the effect of educational program on the severity of the diseaseSkin and Connective Tissue DiseasesPACTR202403515609366Alexandria University30
已完成
不适用
Comparison of psychological and therapeutic treatment on obsessive-compulsive disorder.Obsessive-compulsive disorder.Obsessive-compulsive disorderIRCT2017081335675N1Vice chancellor for research, Kurdistan University of Medical Sciences
已完成
早期 1 期
Investigation the effects of combined exposure to harmful and non-harmful levels of noise, heat and lighting on performance indices such as attention & working memory and physiological indices such as body temperature, blood pressure & heart rate of human, 2013.Condition 1: Attention. Condition 2: Memory. Condition 3: Blood pressure. Condition 4: Body temperature. Condition 5: Heart rate.Profound mental retardationOther symptoms and signs involving cognitive functions and awarenessExamination of blood pressureIRCT2013101415016N1Shiraz University of Medical Sciences128
已完成
不适用
An exploratpry study of the correlation of effects of memantine for cognitive function/BPSD and functional alterations on image of FDG-PET/SPECT in moderate Alzheimer's disease patientModerate Alzheimer's DiseaseJPRN-UMIN000016420Sunagawa City Medical Center30
招募中
不适用
Comparison of the effectiveness of the Exposure and Response Prevention therapy and mindfulness based Exposure and response prevention therapy in people with contamination/washing OCDObsessive Compulsive Disorder.Obsessive-compulsive disorderIRCT20190407043186N1Kashan University of Medical Sciences69