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临床试验/NCT07256132
NCT07256132已完成不适用

The Efficacy of Erector Spinae Plane Block for the Relief of Chronic Pain in Cases of Degenerative Disc Diseases.

Alexandria University1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2022年8月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
40
试验地点
1
主要终点
visual analogue scale

研究概览

简要总结

Erector Spinae Plane Block is an effective pain therapy technique to relieve chronic low back pain in cases of degenerative disc disorders.

详细描述

This study will be conducted on 40 adult patients with degenerative disc disease (DDD) of the lumbar spine and admitted to the Neurosurgery Department at Alexandria Main University Hospital aged between 30 and 65 years old with Visual analog scale more than or equal to 4 not responding to conservative treatment, patients having grade 0, 1 or 2 lumbar disc degeneration without disc bulge or prolapse by X-ray and MRI with loss or decreased lumbar lordosis, patients with black disc and contained disc bulge on magnetic resonance imaging (MRI) and patients with grade I degenerative spondylolisthesis provided that the canal dimensions are normal or with mild stenosis. Patients with severe sciatic pain, patients with more than two levels of DDD of the lumbar region or with isthmic spondylolisthesis and high-grade instability, or patients with disc fragments encroaching upon the exit foramina and nerve root or with severe canal stenosis, also those with central obesity, recurrent disc prolapse or with previous abdominal surgery were excluded from the study. Steroid injection will avoided in patients with immunosuppression or uncontrolled diabetes.

Both a full history taking and a clinical examination will be completed. All patients underwent an MRI of the lumbar region for evaluation. Routine laboratory and other lab investigations will conducted.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Treatment
盲法
Double (Participant, Care Provider)

入排标准

年龄范围
30 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •This study was conducted on 40 adult patients with degenerative disc disease (DDD) of the lumbar spine and admitted to the Neurosurgery Department at Alexandria Main University Hospital aged between 30 and 65 years old with Visual analog scale more than or equal to 4 not responding to conservative treatment, patients having grade 0, 1 or 2 lumbar disc degeneration without disc bulge or prolapse by X-ray and MRI with loss or decreased lumbar lordosis, patients with black disc and contained disc bulge on magnetic resonance imaging (MRI) and patients with grade I degenerative spondylolisthesis provided that the canal dimensions are normal or with mild stenosis

排除标准

  • •Patients with severe sciatic pain, patients with more than two levels of DDD of the lumbar region or with isthmic spondylolisthesis and high-grade instability, or patients with disc fragments encroaching upon the exit foramina and nerve root or with severe canal stenosis, also those with central obesity, recurrent disc prolapse or with previous abdominal surgery were excluded from the study. Steroid injection was avoided in patients with immunosuppression or uncontrolled diabetes.

研究组 & 干预措施

injected patients

Experimental

干预措施: erector spinae plane block (Procedure)

care provider

No Intervention

结局指标

主要结局

visual analogue scale

时间窗: 8 weeks

otal scores range from 0 to 10 (based on a scale of 0 to 2 for five items), with a higher score indicating more severe pain.

次要结局

  • Oswestry disability index(8 weeks)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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