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Clinical Trials/ISRCTN16066516
ISRCTN16066516
Completed
Not Applicable

Early aggressive respiratory therapy and rehabilitation interventions in the role of the prognosis of patients with acute traumatic spinal cord injury and explore oxidative stress, inflammation, DNA damage, leukocyte apoptosis and endothelial dysfunction, and its association with cardiovagal function and cerebral autoregulation

Chang Gung Memorial Hospital0 sites90 target enrollmentOctober 10, 2017
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ConditionsAcute spinal cord injuryInjury, Occupational Diseases, PoisoningInjury of spinal cord, level unspecified

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Acute spinal cord injury
Sponsor
Chang Gung Memorial Hospital
Enrollment
90
Status
Completed
Last Updated
8 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
October 10, 2017
End Date
TBD
Last Updated
8 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Chang Gung Memorial Hospital

Eligibility Criteria

Inclusion Criteria

  • •1\. Acute Spinal Cord Injury (SCI) patients aged 20\-70 years old
  • •2\. Patients will be enrolled in this study only if full informed written consent is obtained from the patient or their families and they qualify for the above\-mentioned diagnostic criteria. The informed written consent will be approved by the Ethics Committee

Exclusion Criteria

  • •1\. Severe multiple trauma with unstable hemodynamic status
  • •2\. Previous brain insults, such as stroke, traumatic intracranial hemorrhage, meningitis, or degenerative brain diseases that cause central nerve system abnormality
  • •3\. Infection or inflammation status before admission
  • •4\. Diffuse atherosclerotic changes on extracranial vessels; hematologic disorders that affect leukocyte, platelet count, or function
  • •5\. Taking antiplatelet or anticoagulation drugs
  • •6\. Major systemic disease, such as end\-stage renal diseases, liver cirrhosis, and congestive heart failure

Outcomes

Primary Outcomes

Not specified

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