Early aggressive respiratory therapy and rehabilitation interventions in the role of the prognosis of patients with acute traumatic spinal cord injury and explore oxidative stress, inflammation, DNA damage, leukocyte apoptosis and endothelial dysfunction, and its association with cardiovagal function and cerebral autoregulation

Chang Gung Memorial Hospital0 个研究点目标入组 90 人开始时间: 2017年10月10日最近更新: 2017年10月30日

适应症

试验速览

暂无简介。

•1. Acute Spinal Cord Injury (SCI) patients aged 20-70 years old
•2. Patients will be enrolled in this study only if full informed written consent is obtained from the patient or their families and they qualify for the above-mentioned diagnostic criteria. The informed written consent will be approved by the Ethics Committee

•1. Severe multiple trauma with unstable hemodynamic status
•2. Previous brain insults, such as stroke, traumatic intracranial hemorrhage, meningitis, or degenerative brain diseases that cause central nerve system abnormality
•3. Infection or inflammation status before admission
•4. Diffuse atherosclerotic changes on extracranial vessels; hematologic disorders that affect leukocyte, platelet count, or function
•5. Taking antiplatelet or anticoagulation drugs
•6. Major systemic disease, such as end-stage renal diseases, liver cirrhosis, and congestive heart failure

发起方

Chang Gung Memorial Hospital