Amantadin as adjuvant therapy in the treatment of moderate to severe OCD
Phase 2
Recruiting
- Conditions
- Obsessive- Cumpulsive Disorder.Obsessive-compulsive disorder
- Registration Number
- IRCT201705191556N99
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Inclusion Criteria: 1- Age between 18-60 years old; 2- Diagnosis of OCD based on DSM-5; 3- Minimum Score of 21 on YALE-BROWN Obsessive-Compulsive Scale.
Exclusion Criteria
1- Substance dependence; 2- IQ <70; 3- Any other mental disorder on axis I; 4-Any serious cardiac, renal or hepatic disease; 5- receiving psychotropic medications during the last 6 weeks; 6- pregnancy or breast feeding; 7- Rising liver transaminases to three times the upper limit of normal or higher.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of symptoms of OCD. Timepoint: Baseline and weeks: 2, 4, 6, 8, 10 after beginig of treatment. Method of measurement: Y_BOCS( Yale-Brown obsessive compulsive scale).
- Secondary Outcome Measures
Name Time Method