MedPath

Patient Augmented Reality and Vibratory Array Otorhinolaryngology Procedures

Not Applicable
Recruiting
Conditions
Laryngeal Neoplasms
Vocal Fold Polyp
Pain, Acute
Vocal Cord Paralysis
Interventions
Other: Augmented Reality on
Other: Vibroacoustic stimulation on
Other: Augmented reality off
Other: Vibroacoustic stimulation off
Registration Number
NCT06227039
Lead Sponsor
University of Virginia
Brief Summary

In-office procedures (IOPs) are a cost-effective, and safe alternative to many operating room procedure, with benefits such as reduced anesthesia risk. One of the major causes of failed in-office procedures or requirement of conversion to the operating room is poor patient tolerance. Vibration and augmented reality (AR) can be used as non-pharmacologic treatment options to treat patient anxiety and pain by using the physiology proposed by the gate-way theory of pain as well as distraction. This study seeks to compare anxiety and pain perception with patient reported survey data, as well as physiologic indicators of stress such as heart rate variability (HRV) within patients undergoing IOPs in a laryngology office with and without vibration and AR treatment.

Detailed Description

In-office procedures (IOPs) represent a cost-effective and safe alternative to operating room procedures for a myriad of disease processes across medical and surgical specialties. IOPs are performed under local anesthetic without general anesthesia or sedation, resulting in faster and often safer procedures by eliminating risks associated with general anesthesia. IOPs are primarily limited by patient tolerance, as there is a lack of currently available non-pharmacologic treatment options for patient anxiety, stress, discomfort, and pain during these procedures.

The Gate Control Theory of Pain postulates that only a limited amount of simultaneous sensory stimuli can be processed by the central nervous system and therefore non-painful stimuli, such as vibration or virtual distraction (i.e. virtual or augmented reality), can eliminate or lessen the perception of concurrent painful stimuli. The use of these non-painful stimuli has been shown to have clinical utility in the setting of procedures such as percutaneous injections and wound dressing changes.

However, the coupling of multiple sensory distraction techniques has not been described for IOPs. Furthermore, no investigation of sensory distraction techniques to reduce patient discomfort within the field of otolaryngology has been conducted. The focus of the proposed project is to improve patient experience during IOPs by coupling a novel vibroacoustic stimulation device with original AR software applications.

In-office otolaryngology procedures specifically involve using a rigid endoscope or a flexible nasolarynogoscopy to visualize the inside of a patient nose, sinus, posterior oropharynx, and vocal cords. Using these imaging modalities, awake, in-office procedures can be performed. However, these procedures are often very uncomfortable and anxiety producing.

The goal of the study is to determine whether or not wearing an augmented reality headset with a novel game and vibroacoustic simulation device can help reduce anxiety and improve the patient experience of in-office otolaryngology procedures. The device consists of an augmented reality headset worn by the patient, a vibration device that is applied to the patient's neck to help reduce the sensation of the procedure, and a clicker that allows the patient to interact with the augmented reality game environment.

Patients who are undergoing in-office laryngology procedures (procedures on their vocal cords) will be randomized into a control group augmented reality (AR) group, vibration group, and combined AR and vibration group. The control group will wear a sham augmented reality head set during the procedure. The AR group will have a game played on the head set to distract them during the procedure. The patient will interact with the game use a hand held clicker.

Each participant will answer a survey before and after the procedure assessing their anxiety. Each participant will also wear a one-lead EKG to measure their heart rate through the procedure. The subjective and physiological level will be compared between the two groups

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
80
Inclusion Criteria
  • Patients undergoing office-based laryngology procedure performed at home institution.
Exclusion Criteria
  • None

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Augmented RealityAugmented Reality onThis arm will use the augmented reality game to provide a visual stimulus to the patient as treatment to reduce pain and anxiety. Vibroacoustic device will be worn but will be turned off.
Combination vibroacoustic and augmented realityVibroacoustic stimulation onThis arm will use both the augmented reality game and vibroacoustic device to provide a visual stimulus to the patient as treatment to reduce pain and anxiety.
VibroacousticAugmented reality offThis arm will use the vibroacoustic device to provide a mechanical stimulus to the patient as treatment to reduce pain and anxiety. Augmented reality glasses will be worn but will be turned off.
VibroacousticVibroacoustic stimulation onThis arm will use the vibroacoustic device to provide a mechanical stimulus to the patient as treatment to reduce pain and anxiety. Augmented reality glasses will be worn but will be turned off.
Combination vibroacoustic and augmented realityAugmented Reality onThis arm will use both the augmented reality game and vibroacoustic device to provide a visual stimulus to the patient as treatment to reduce pain and anxiety.
Augmented RealityVibroacoustic stimulation offThis arm will use the augmented reality game to provide a visual stimulus to the patient as treatment to reduce pain and anxiety. Vibroacoustic device will be worn but will be turned off.
Primary Outcome Measures
NameTimeMethod
Average pain experiencedmeasured post-treatment (1 hr).

Visual analog scale rating of average perceived pain during procedure

Pain nervousness experiencedmeasured post-treatment (1 hr).

Visual analog scale rating of how nervous about pain patient was during procedure

Max pain experiencedmeasured post-treatment (1 hr).

Visual analog scale rating of max perceived pain during procedure

Change in heart rate variability during procedurecalculated post-treatment (1 hr).

Difference between heart rate variability during procedure compared with pre-procedure

Change in average heart ratecalculated post-treatment (1 hr).

Difference between average heart rate during procedure compared with pre-procedure

Time spent thinking about painmeasured post-treatment (1 hr).

Visual analog scale rating of percent of time spent thinking about pain during procedure

Change in maximum heart ratecalculated post-treatment (1 hr).

Difference between maximum heart rate during procedure compared with pre-procedure

Secondary Outcome Measures
NameTimeMethod
Pain catastrophizing scorecalculated pre-procedure (1 hr).

Pain catastrophizing score

Change is STAI scorecalculated post-procedure (1 hr).

Measure change in Stait-Trait anxiety inventory State 5 question score pre and post-procedure.

Patient satisfactionmeasured post-treatment (1 hr).

Likert scale rating of satisfaction of treatment group

Trial Locations

Locations (1)

UVA Fontaine Research Park Building 415

🇺🇸

Charlottesville, Virginia, United States

© Copyright 2025. All Rights Reserved by MedPath