NL-OMON33652已完成不适用
An observational study to obtain normal values of inflammatory variables in induced sputum, exhaled breath, and bronchial biopsies from healthy smoking and non-smoking individuals - The NORM study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •1. Doctor*s diagnosis of normal pulmonary health
- •2. Post bronchodilator FEV1/FVC >70%
- •3. PC20 methacholine >12 mg/ml
- •4. Reversibility of FEV1% predicted <10%
排除标准
- •1. Persons who used inhaled or oral corticosteroids during >5 years, or
- •within the last 5 years.
- •2. FEV1 <1.2 L,
- •3. A subject is not eligible to enter and participate if he does not agree
- •that we inform his general practicioner about participation in the study and also
- •about any unexpected finding during the study.
- •4. Upper respiratory tract infection (e.g. colds), within 2 months.
- •5. Pregnancy, or the possibility of being pregnant (i.e. women who do not use adequate anticonception as judged by the investigator).
- •6. Malignancy within the past 5 years (except for squamous or basal cell carcinoma
- •of the skin that has been treated with no evidence of recurrence).
- •7. Signs or symptoms of any other concomitant disease that, in the eyes of the
- •investigator, can interfere with the study results.
- •8. Known recent substance abuse (drug or alcohol).
- •9. Claustrophobia
研究者
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