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临床试验/NCT07450560
NCT07450560进行中(未招募)不适用

Full-Digital PET Enables Real-time Monitoring of Proton Range

Shuanghu Yuan1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2026年2月1日最近更新:

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
30
试验地点
1
主要终点
the trajectory and range of the proton beam within the human body

研究概览

简要总结

The energy transport process of proton beams after entering biological tissue is observed online via proton knife fully digital PET. The dynamic changes of the delivered dose and action range of proton beams in biological tissue are analyzed, the proton dose distribution is reconstructed, and the energy and position of the targeted ablation by proton beams are determined, so as to realize in-beam online PET monitoring for proton therapy.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients with solid tumors scheduled to receive proton therapy, with measurable lesions;
  • Signed the informed consent form.

排除标准

  • Patients with a history of radioactive seed implantation;
  • Patients who cannot understand the purpose of treatment or are unwilling/unable to sign the informed consent form;

结局指标

主要结局

the trajectory and range of the proton beam within the human body

时间窗: 1 day

the three-dimensional dynamic distribution of positron nuclides generated by proton beam irradiation

次要结局

未报告次要终点

研究者

发起方
Shuanghu Yuan
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Shuanghu Yuan

Principal Investigator

Anhui Provincial Cancer Hospital

研究点 (1)

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