Personality Traits and Its Impact on Quality of Life and Clinical Outcome Evaluation in Patients With Crohn's Disease
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Crohn's Disease
- Sponsor
- Jinling Hospital, China
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- IBDQ
- Last Updated
- 12 years ago
Overview
Brief Summary
Quality of life is recommended as one of essential parameters to evaluate treatment effect and clinical outcome in patients with Crohn's disease (CD). Recent studies reported that several disease-unrelated variables may affect quality of life in CD patients. This study is dedicated to investigate the influence of various personality traits on quality of life, and whether or not they should be taken into account when evaluating clinical outcomes in patients with CD.
Detailed Description
This is a prospective, single-center study. All enrolled patients are divided into 2 groups: * Group 1: quiescent CD group (CDAI≤150 points) * Group 2: active CD group (CDAI\>150 points) All enrolled patients are required to accomplish the following questionnaires at visit: * Inflammatory Bowel Disease Questionnaire (IBDQ) * Neuroticism (N) and Lie (L) subscale of the Eysenck Personality Inventory (EPI) * Hospital Anxiety and Depression Scale (HADS) * Buss-Perry Aggression (BPA) questionnaire All questionnaires are translated and validated in Chinese population.
Investigators
Jianan Ren
Vice president of department of surgery, Jinling Hospital
Jinling Hospital, China
Eligibility Criteria
Inclusion Criteria
- •18-65 years old
- •a definite diagnosis of CD
Exclusion Criteria
- •current or previous mental disorders
- •receiving or once received psychotherapy
- •presence of major medical conditions (such as necessity of an operation)
- •chronic disease history other than inflammatory bowel disease
- •unwilling to participate in or cannot accomplish current study
Outcomes
Primary Outcomes
IBDQ
Time Frame: one week
Inflammatory Bowel Disease Questionnaires (IBDQ) is the most widely used and validated disease-specific instrument, which contains 32 items and assesses four aspects (subscales) of quality of life: emotional function (12 items), social function (5 items), bowel function (10 items) and systemic symptom (5 items).
Secondary Outcomes
- Eysenck Personality Inventory (EPI)(one week)
- Hospital Anxiety and Depression Scale (HADS)(one week)
- Buss Perry Aggregation (BPA) questionnaire(one week)