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Clinical Trials/ISRCTN50980108
ISRCTN50980108
Completed
未知

Detecting and managing undernutrition in adults with inactive Crohn's Disease: feasibility randomised comparative trial of oral nutritional support

King's College London (UK)0 sites7 target enrollmentJanuary 31, 2014

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
King's College London (UK)
Enrollment
7
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
January 31, 2014
End Date
September 30, 2014
Last Updated
5 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
King's College London (UK)

Eligibility Criteria

Inclusion Criteria

  • 1\. Men and women aged \=18 years
  • 2\. Diagnosis of Crohn's disease for duration of at least 6 months confirmed by standard clinical, histological and radiological criteria
  • 3\. Crohn's disease in remission as defined by Harvey Bradshaw score of \< 5
  • 4\. Stable medications (see exclusion criteria), no recent surgery (see exclusion criteria) and stable symptoms for at least 2 months
  • 5\. BMI \< 20 kg/m2
  • 6\. A willingness to participate
  • 7\. Individuals able to give informed consent

Exclusion Criteria

  • 1\. Patients with active Crohn's disease
  • 2\. Use of the following treatments: antibiotics, non\-steroidal anti\-inflammatory drugs (NSAIDs) during the preceding week
  • 3\. Currently taking steroids
  • 4\. Recent changes in dose to the following treatments: azathioprine, 6\-mercaptopurine, methotrexate or a\-TNF agents during the preceding 12 weeks, oral 5\-aminosalicylate (5\-ASA) or steroids during the preceding 4 weeks
  • 5\. Previous pan\-proctocolectomy, pure perianal disease or short bowel syndrome
  • 6\. Stenotic disease
  • 7\. Sepsis or fever
  • 8\. Diabetes or coeliac disease (by serology and/or duodenal biopsy)
  • 9\. Other concomitant serious comorbidity e.g. significant hepatic, renal, endocrine, respiratory, neurological or cardiovascular disease
  • 10\. Pregnancy or lactation

Outcomes

Primary Outcomes

Not specified

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