Mechanisms and Long-term Effects of Separate vs. Coupled Rehabilitation Approaches After Stroke
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Cortical reorganization and kinematic analysis
研究概览
简要总结
Identify the possible mechanisms and the relative effectiveness of existing rehabilitation approaches that target upper extremity deficits of stroke patients on the ground that these approaches are based on neuroplasticity principles and sound motor control theories.
详细描述
Comparisons of constraint-induced therapy (CIT) vs. bilateral arm training (BIT)vs. combined therapy were made. Stroke patients will receive one of these three approaches and be evaluated pre- and post-treatment. the treatment will last 3 weeks and 5 days per week. The evaluation will include clinical measures of motor function, ADL, and quality of life, kinematic performance, and activation patterns of cortex.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •a first-ever clinical cerebrovascular accident patients
- •at least 6 months post-stroke onset
- •premorbid right-hand dominance
- •demonstration of Brunnstrom stage III of the affected upper extremity
- •no excessive spasticity in the joints of the affected upper extremity
排除标准
- •a score of less than 24 on the Mini Mental State Exam
- •poor physical conditions that would interfere with participation
- •excessive pain in any joint that might limit participation
研究组 & 干预措施
3
combined therapy
干预措施: Combined therapy (CT) (Other)
Control intervention
干预措施: Control intervention (Behavioral)
1
constraint-induced therapy
干预措施: Constraint-induced therapy (CIT) (Other)
2
bilateral arm training
干预措施: Bilateral arm training (BAT) (Other)
结局指标
主要结局
Cortical reorganization and kinematic analysis
时间窗: 2008-2010
次要结局
- clinical measures at the impairment, activity, participation levels(2008-2010)