Sunscreen Removal by Clothing Meassured in Vivo. Sun Protection Factor Persistence During a Day Indoor Without Physical Activity. Does Sunscreen Reduce Vitamin D?
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Bispebjerg Hospital
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- vitamin D (nmol) meassured in a blood sample.
Study Overview
Brief Summary
The investigators want to investigate whether sunscreen is removed by clothing and to what extend when the amount of sunscreen applied varies.Does clothing reduce the SPF when clothes are put on 20, 8, or 4 minutes after sunscreen application? The investigators also want to investigate the persistence of sunscreen during eight hours indoor. How much does the SPF reduces? Furthermore, we want to investigate whether sunscreen in the layers 2, 1, and 0.5 mg/cm2 reduce the vitamin D production in the skin.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Factorial
- Primary Purpose
- Prevention
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Healthy participants.
- •> 18 years.
- •Skin type I, II, and III.
Exclusion Criteria
- •Pregnancy.
- •Medicin use.
- •Skin or other diseases.
- •The participants must not have been in solarium or gotten sun on their trunks in the 3 months before the study start and during the study.
- •Skin types IV and above.
Arms & Interventions
4
Sunscreen applied 2mg/cm2
Intervention: sunscreen MATAS sunlotion SPF 8 (Other)
4
Sunscreen applied 2mg/cm2
Intervention: UVB light (Radiation)
1
No sunscreen applied
Intervention: UVB light (Radiation)
2
Sunscreen applied 0.5 mg/cm2
Intervention: UVB light (Radiation)
3
Sunscreen applied 1mg/cm2
Intervention: UVB light (Radiation)
Outcomes
Primary Outcomes
vitamin D (nmol) meassured in a blood sample.
Time Frame: 5 days after sunscreen use and UV light exposure
Secondary Outcomes
No secondary outcomes reported