A Prospective Study of the Effects of Pregabalin versus Placebo on the incidence and intensity of pain after video-assisted thoracoscopic surgery.

Phase 4

Active, not recruiting

• Conditions: post thoracotomy pain syndrome; Anaesthesiology - Pain management

• Registration Number: ACTRN12614000554662
• Lead Sponsor: Dr Alex Konstantatos

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-05-23
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 95

Inclusion Criteria

Patients having video assisted thoracoscopic surgery (VATS)
Conscious
Able to understand use of PCA ( Patient Controlled Analgesia)

Exclusion Criteria

Morphine or paracetamol contraindication or allergy
Allergy to pregabalin
History of chronic pain
Evolving myocardial infarction, arrhythmias at time of surgery
Preoperative respiratory function tests showing a forced vital capacity<60% predicted, forced expiratory volume 1s <60%, or both
Renal insufficiency (creatinine >15mg/dL)
Liver dysfunction (aspartate aminotransferase, alanine aminotransferase, or both >40u/L)

Study & Design

• Study Type: Interventional
• Study Design: Not specified