Investigating the effect of fentanyl with the combination of morphine, ketamine and lidocaine in pain after open heart surgery

Phase 2

• Conditions: Heart failure.; Combined systolic (congestive) and diastolic (congestive) heart failure; I50.4

• Registration Number: IRCT20231227060539N1
• Lead Sponsor: Bandare-abbas University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 March 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Candidates for elective CABG surgery
Patients 30-80 years old
Anesthesia class II, III
Not receiving painkillers within 6 hours before surgery
surgeryConsent to participate in the study
EF > 40%
Patients without a history of renal, hepatic, gastrointestinal, or pulmonary failure
No alcohol or drug addiction

Exclusion Criteria

Pump time more than 120 minutes
Simultaneous valve and CABG
CABGReoperation to control bleeding and progressive heart failure (requiring high dose postoperative inotropes or IABP)
Emergency surgery

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Measurement of pain score in patients undergoing cabg. Timepoint: Pain score in hours 1, 2, 6, 12 after cabg patients. Method of measurement: Numeric rating scale for pain.

Secondary Outcome Measures

Name	Time	Method
The level of patient satisfaction. Timepoint: 1, 2, 6, 12 hours after surgery. Method of measurement: Visual analogue scale.;Average systolic blood pressure. Timepoint: 1,2,6,12 hours after surgery. Method of measurement: Blood pressure cuff.;Average diastolic blood pressure. Timepoint: 1,2,6,12 hours after surgery. Method of measurement: Blood pressure cuff.;Average mean arterial pressure. Timepoint: 1,2,6,12 hours after surgery. Method of measurement: Blood pressure cuff.;Average heart rate. Timepoint: 1,2,6,12 hours after surgery. Method of measurement: Chest lead monitoring.;Average pain of patients. Timepoint: 1,2,6,12 hours after surgery. Method of measurement: Numeric rating scale.