Comparative evaluation of lactobacillus salivarius probiotic gel and chlorhexidine gel as an adjunct to scaling and root planing.
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- Measurement of clinical attachment level
研究概览
简要总结
This study is a randomized, parallel group clinical trial comparing the efficacy of lactobacillus salivarus probiotic gel and chlorhexidine gel as an adjunct to scaling and root planing in the management of stage two periodontitis patients. probiotic Lactobacillus salivarius has the potential to modify the oral environment through antagonism to bacteria responsible for periodontal inflammation, including bacteria of the red complex. Patients will be assessed for eligibility. Based on Inclusion and Exclusion criteria, At the initial visit, all the patients will receive Supra gingival Scaling. Patients will be recalled after one week and clinical parameters such as plaque index, gingival index, pocket depth and clinical attachment level will be recorded and subgingival scaling and root planning will be performed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 55.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients with age 30 to 55 years Not having received periodontal treatment for a minimum of 3 months prior to the study Persistent periodontal pockets characterized by a PD greater than or equal to 5mm with positive BOP at baseline Patients willing to participate in the study Patients who are apparently healthy.
排除标准
- •Presence of any systemic disease Pregnant women and lactating mothers Use of any form of tobacco Having history of drug usage and allergy Patients who are under periodontal therapy from the past 6 months.
结局指标
主要结局
Measurement of clinical attachment level
时间窗: Baseline and after 3 months
次要结局
- Measurement of probing depth, Plaque index and Sulcular bleeding index(Baseline and after 3 months)
研究者
Golapala Naga Aishwarya
Sibar institute of dental sciences guntur
