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临床试验/CTRI/2025/09/094730
CTRI/2025/09/094730已完成4 期

Comparative evaluation of lactobacillus salivarius probiotic gel and chlorhexidine gel as an adjunct to scaling and root planing.

Golapala Naga Aishwarya1 个研究点 分布在 1 个国家目标入组 48 人开始时间: 2025年10月13日最近更新:

试验速览

阶段
4 期
状态
已完成
发起方
入组人数
48
试验地点
1
主要终点
Measurement of clinical attachment level

研究概览

简要总结

This study is a randomized, parallel group clinical trial comparing the efficacy of lactobacillus salivarus probiotic gel and chlorhexidine gel as an adjunct to scaling and root planing in the management of stage two periodontitis patients. probiotic Lactobacillus salivarius has the potential to modify the oral environment through antagonism to bacteria responsible for periodontal inflammation, including bacteria of the red complex. Patients will be assessed for eligibility. Based on Inclusion and Exclusion criteria, At the initial visit, all the patients will receive Supra gingival Scaling. Patients will be recalled after one week and clinical parameters such as plaque index, gingival index, pocket depth and clinical attachment level will be recorded and subgingival scaling and root planning will be performed.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
None

入排标准

年龄范围
30.00 Year(s) 至 55.00 Year(s)(—)
性别
All

入选标准

  • Patients with age 30 to 55 years Not having received periodontal treatment for a minimum of 3 months prior to the study Persistent periodontal pockets characterized by a PD greater than or equal to 5mm with positive BOP at baseline Patients willing to participate in the study Patients who are apparently healthy.

排除标准

  • Presence of any systemic disease Pregnant women and lactating mothers Use of any form of tobacco Having history of drug usage and allergy Patients who are under periodontal therapy from the past 6 months.

结局指标

主要结局

Measurement of clinical attachment level

时间窗: Baseline and after 3 months

次要结局

  • Measurement of probing depth, Plaque index and Sulcular bleeding index(Baseline and after 3 months)

研究者

发起方
Golapala Naga Aishwarya
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Golapala Naga Aishwarya

Sibar institute of dental sciences guntur

研究点 (1)

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