Effectiveness and cost-effectiveness of a novel rehabilitation strategy in people undergoing primary total knee replacement surgery. The MARKER (Maximum Recovery After Knee Replacement Surgery) Study.

Recruiting

• Conditions: Primary total knee replacement surgery for osteoarthritis; Musculoskeletal - Osteoarthritis

• Registration Number: ACTRN12609000054213
• Lead Sponsor: Dr Marlene Fransen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-01-23
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

undergoing unilateral or bilateral primary total knee replacement surgery, able to provide informed consent, able to be discharged home from the orthopaedic ward

Exclusion Criteria

(i) previous unicompartmental replacement or tibial osteotomy on the same knee, (ii) previous lower limb joint replacement surgery within the last six months, (iii) further lower limb joint replacement surgery anticipated within the next 12 months, (iv) major co-morbidity precluding aerobic exercise at 50-60% maximum heart rate, (v) rheumatoid arthritis, (vi) major neurological conditions, or (vii) inability to return to one of the participating sites for outpatient exercise classes

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain subscale on the Western Ontario and McMaster Universities (WOMAC) Scale (pain in the knee over the last 48 hours)[6 weeks, 6 months and 12 months after randomisation];Physical function subscale on the Western Ontario and McMaster Universities (WOMAC) Scale (difficulties in physical activities in the knee over the last 48 hours)[6 weeks, 6 months and 12 months after randomisation]