Reducing Healthcare Costs in Older Adults by Deprescribing Unnecessary, Harmful, and Costly Medications
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 419
- 试验地点
- 2
- 主要终点
- Healthcare Cost
研究概览
简要总结
The purpose of the study is to implement a pharmacist-led deprescribing intervention for adults 65 and older taking 10 or more medications at University of Texas (UT) Physicians clinics and to assess the effect of the pharmacist intervention on the incidence of adverse drug reactions, emergency room visits, and hospitalizations as well as costs to the patient and to the healthcare system in adults 65 and older taking 10 or more medications treated at UT Physicians.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- taking 10 or more regular medications
排除标准
- •not receiving primary care at UT Physicians
结局指标
主要结局
Healthcare Cost
时间窗: 12 months post enrollment
Healthcare cost based on utilization of clinic visits, emergency room visits, and hospitalizations, based on patient report with specific costs obtained when possible from the Health Information Exchange.
Adverse Drug Reactions
时间窗: 12 months post enrollment
Patient-reported side effects and adverse events potentially attributable to medication, rated for the likelihood of ADR by an independent reviewer based on the Naranjo algorithm.
Adverse Drug Reactions (ADR)
时间窗: 3 months post enrollment
Patient-reported side effects and adverse events potentially attributable to medication, rated for the likelihood of ADR by an independent reviewer based on the Naranjo algorithm.
次要结局
- Medication cost(12 months post enrollment)
- Medication use(At enrollment)
- QOL(12 months post enrollment)
研究者
Holly M Holmes
Associate Professor
The University of Texas Health Science Center, Houston