Study on the Prognosis and Effect of Anti-diabetic Drugs on Type-2 Diabetes Mellitus With Coronary Artery Disease
Phase 4
Completed
- Conditions
- Type 2 DiabetesCoronary Artery Disease
- Interventions
- Registration Number
- NCT00513630
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Brief Summary
The purpose of this study is to explore the recurrence risk of cardiovascular events in patients with type 2 diabetes mellitus and coronary heart disease after different antidiabetic drug therapy (glipizide or metformin) by using an double-blind, randomized, parallel control and prospective study
The end point of this study is:
1. follow up 3yr
2. recurrence of cardiovascular event
3. death caused by other reasons such as stroke, uremia, blindness and amputation
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 304
Inclusion Criteria
- Coronary heart disease
- Type 2 diabetes
Exclusion Criteria
- Severe organ dysfunction, psychopathy, infection, neutropenia
- Congenital heart disease, rheumatic heart disease, severe arrhythmia, myocardiopathy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description metformin Glipizide - glipizide Metformin -
- Primary Outcome Measures
Name Time Method Composite of cardiovascular events which were defined as death from a cardiovascular cause, death from any cause, nonfatal myocardial infarction, nonfatal stroke or arterial revascularization
- Secondary Outcome Measures
Name Time Method New or worsening angina new or worsening heart failure new critical cardiac arrhythmia new peripheral vascular events
Trial Locations
- Locations (1)
Shanghai Jiao Tong University School of Medicine
🇨🇳Shanghai, China