Administration of warm blood cardioplegia with or without roller pump; a comparison.
Completed
- Conditions
- CABGcoronary artery bypass grafting1001108210007593
- Registration Number
- NL-OMON37560
- Lead Sponsor
- Heartbeat
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 68
Inclusion Criteria
- Patients undergoing elective coronary artery bypass grafting
- At least 3 distal anastomosis will be performed
Exclusion Criteria
- Previous cardiac surgery
- Left ventricular ejection fraction <45%
- Chronic renal failure, defined by preoperative creatinine > 177 ug/ml.
- Aortic Insufficiency, >= grade 1
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Perioperative myocardial injury, reflected by biomarker release:<br /><br>- Troponin I<br /><br>- hFABP<br /><br>- NT-pro-BNP</p><br>
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms of warm blood cardioplegia in CABG surgery?
How does pumpless blood cardioplegia compare to standard warm blood cardioplegia in CABG outcomes?
Which biomarkers predict optimal response to warm blood cardioplegia in coronary artery bypass patients?
What are the potential adverse events associated with roller pump-free cardioplegia delivery systems?
Are there combination therapies or alternative approaches to warm blood cardioplegia for improving myocardial protection in CABG?